Article
Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis.
Biological psychiatry - 15 Sept 2007
Job Martin O, Tang Amanda, Hall F Scott, Sora Ichiro, Uhl George R, Bergeson Susan E, Gonzales Rueben A
Abstract excerpt
BACKGROUND: Ethanol stimulates the dopaminergic mesoaccumbal pathway, which is thought to play a role in ethanol reinforcement. Mu (mu)-opioid (MOP) receptors modulate accumbal dopamine activity, but it is not clear whether MOP receptors are involved in the mechanism of ethanol-stimulated accumbal dopamine release. METHODS: We investigated the role that MOP receptors play in ethanol (2.0 g/kg)-stimulated accumbal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
