Article
Alternative splicing and bioinformatic analysis of human U12-type introns.
Nucleic acids research - 1 Jan 2007
Chang Wen-Cheng, Chen Yung-Chia, Lee Kuo-Ming, Tarn Woan-Yuh
Abstract excerpt
U12-type introns exist, albeit rarely, in a variety of multicellular organisms. Splicing of U12 intron-containing precursor mRNAs takes place in the U12-type spliceosome that is distinct from the major U2-type spliceosome. Due to incompatibility of these two spliceosomes, alternative splicing involving a U12-type intron may give rise to a relatively complicated impact on gene expression. We studied alternative...
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