Article
Identification of sequence elements containing signals for replication and encapsidation of the reovirus M1 genome segment.
Virology - 1 Feb 1992
Zou S, Brown E G
Abstract excerpt
In reovirus the genetic signals that control genome replication and encapsidation are unknown. Serial passage of reovirus results in the accumulation of deletion mutants that contain fragments of genome segments. The smallest fragments found in deletion mutants will consist of the minimum essential sequences for genome replication and assembly. T1 x T3 reassortants containing the L2 segment from T3 and the M3...
Topics
- Base Sequence
- Blotting, Northern
- Capsid
- Cloning, Molecular
- Electrophoresis, Polyacrylamide Gel
- Genome, Viral
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Viral
- Reoviridae
