Article

Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage

2020-10-19

Abstract excerpt

<h4>ABSTRACT</h4> For viruses with segmented genomes, genetic diversity is generated by genetic drift, reassortment, and recombination. Recombination produces RNA populations distinct from full-length gene segments and can influence viral population dynamics, persistence, and host immune responses. Viruses in the Reoviridae family, including rotavirus and mammalian orthoreovirus (reovirus), have been reported to...

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Literature Corpus work: 89bf3e6b-6692-5c9b-8610-d8a57ddd922b
DOI: 10.1101/2020.10.19.346031

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