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Article

Dual-probe assay for detection of lamivudine-resistance hepatitis B virus by real-time PCR.

Journal of virological methods - 1 Mar 2006

Geng Haifeng, Hua Bing, Wang Hua, Cao Yanhong, Sun Yun, Yu Airong

Abstract excerpt

A rapid and accurate minor groove binder (MGB) real-time PCR is described for detection lamivudine resistance mutations in hepatitis B virus. The real-time PCR was compared with direct Sanger sequencing in 53 clinical patients samples, the results of the real-time PCR correlate with the nucleotide sequence and the assay has the advantage of detecting a mixture of quasi-species with higher sensitivity than...

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Share to Antiviral Agents
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Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis B virus

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Source

Identifiers

PMID: 16198006
DOI: 10.1016/j.jviromet.2005.08.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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