Article
The influence of three endothelin-1 polymorphisms on the progression of IgA nephropathy.
Folia biologica - 1 Jan 2007
Maixnerová D, Merta M, Reiterová J, Stekrová J, Rysavá R, Obeidová H, Viklický O, Potmĕsil P, Tesar V
Abstract excerpt
The clinical course of chronic renal diseases and their progression to ESRF is highly variable. Different candidate gene polymorphisms have been advocated as possible modulators of ESRF progression. Moreover, ET-1 has been suggested as a major promoting factor in renal disease. However, limited data are available regarding an association of three ET-1 SNP K198N, T- 1370G and 3A/4A with the progression of IgAN to...
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