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Article

The influence of two megsin polymorphisms on the progression of IgA nephropathy.

Folia biologica - 1 Jan 2008

Maixnerová D, Merta M, Reiterová J, Stekrová J, Rysavá R, Viklický O, Obeidová H, Tesar V

Abstract excerpt

The clinical course of chronic renal diseases and their progression to ESRD is highly variable. The strongest predictors of poor outcome of IgAN involve hypertension, severe proteinuria and elevated serum creatinine level. Different candidate gene polymorphisms have been advocated as possible modulators of the progression of IgAN. Megsin belongs to the serpin superfamily and was mapped to chromosome 18q21.3....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, IGA

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Share to Polymorphism, Single Nucleotide

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Source

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PMID: 18498720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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