Article
The influence of endothelin-A receptor gene polymorphism on the progression of autosomal dominant polycystic kidney disease and IgA nephropathy.
Folia biologica - 1 Jan 2007
Reiterová J, Merta M, Stekrová J, Maixnerová D, Obeidová H, Kebrdlová V, Viklický O, Tesar V
Abstract excerpt
ADPKD is the most common hereditary renal disease. IGAN is a mesangial proliferative glomerulonephritis characterized by diffuse mesangial deposition of immunoglobulin A. ET-1 has been suggested to be a major disease-promoting factor in renal diseases. The vasoconstrictor effect of ET-1 is mediat...
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