Article
Analysis of three genetic markers in IgA nephropathy patients from a single region.
Clinical nephrology - 1 Apr 2002
Drouet M, Aupetit C, Denizot Y, Bois M, Bridoux F, Aldigier J C, Cogné M
Abstract excerpt
BACKGROUND: IgA nephropathy (IgA-N) is the most common glomerular disease. Various genetic factors have been suspected to influence the disease, but they never have been studied in the same cohort of patients. METHODS: In 125 IgA-N biopsy-proven cases, we studied by DNA techniques the allele distribution of 3 polymorphic loci: the angiotensin-converting enzyme (ACE) gene, the specific HLA-DQB1 gene and the hs1,2...
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