Article
Associations of genetic variations of the endothelial nitric oxide synthase gene and environmental carcinogens with oral cancer susceptibility and development.
Nitric oxide : biology and chemistry - 1 Sept 2018
Su Chun-Wen, Chien Ming-Hsien, Lin Chiao-Wen, Chen Mu-Kuan, Chow Jyh-Ming, Chuang Chun-Yi, Chou Chia-Hsuan, Liu Yu-Cheng, Yang Shun-Fa
Abstract excerpt
Oral cancer is a major head and neck cancer that is reported to be causally associated with genetic factors and environmental carcinogens. Endothelial nitric oxide synthase (eNOS) was reported to modulate carcinogenesis and progression through nitric oxide (NO) production. Genetic polymorphisms in the eNOS gene can regulate its transcription and further mediate NO production. The purpose of this study was to...
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