Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a candidate genetic variant for the high prevalence of type II diabetes in Polynesians.

European journal of human genetics : EJHG - 1 May 2007

Myles Sean, Hradetzky Eva, Engelken Johannes, Lao Oscar, Nürnberg Peter, Trent Ronald J, Wang Xingyu, Kayser Manfred, Stoneking Mark

Abstract excerpt

The prevalence of non-insulin-dependent diabetes mellitus (type II diabetes) in Polynesia is among the highest recorded worldwide and is substantially higher than in neighboring human populations. Such large differences in the frequency of a phenotype between populations may be explained by large allele frequency differences between populations in genes associated with the phenotype. To identify genes that may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Proteins

Share to Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

Share to Polynesia

Share to Population

Share to Prevalence

Share to Transcription Factors

Source

Identifiers

PMID: 17327880
DOI: 10.1038/sj.ejhg.5201793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a candidate genetic variant for the high prevalence of type II diabetes in Polynesians.PMID 17327880Read ↗

Differences in disease frequency between Europeans and Polynesians: directions for future research into genetic risk factors.Semantic proximity Read ↗

Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans.Semantic proximity Read ↗

Unravelling the determinants of human health in French Polynesia: the MATAEA projectSemantic proximity Read ↗

The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians.Semantic proximity Read ↗

The impact of global and local Polynesian genetic ancestry on complex traits in Native HawaiiansSemantic proximity Read ↗

Differences in disease frequency between Europeans and Polynesians: directions for future research into genetic risk factors.Semantic proximity Read ↗

Polygenic and single-locus selection on BMI during Polynesian expansion.Semantic proximity Read ↗

Comparative study of polymorphisms on genes associated with lifestyle related diseases in Asian and Pacific populations.Semantic proximity Read ↗

Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A.Semantic proximity Read ↗

Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus.Semantic proximity Read ↗

Hypertension-susceptibility gene prevalence in the Pacific Islands and associations with hypertension in Melanesia.Semantic proximity Read ↗

Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.