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Article

Genetic variation in mouse beta globin cysteine content modifies glutathione metabolism: implications for the use of mouse models.

Experimental biology and medicine (Maywood, N.J.) - 1 Mar 2007

Hempe James M, Ory-Ascani Jeannine, Hsia Daniel

Abstract excerpt

Allelic variation in the mouse beta globin gene complex (Hbb) produces structurally different beta globins in different mouse strains. Like humans, mice with HbbS alleles produce a single beta globin with one reactive cysteine (beta Cys93). In contrast, mice with HbbD alleles produce two structurally different beta globins, each containing an additional cysteine (beta Cys13). beta Cys93 forms mixed disulfides...

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PMID: 17327478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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