Article
O2-induced changes in lung and storage pool thiols in mice: effect of superoxide dismutase.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Mar 1993
Rusakow L S, White C W, Stabler S P
Abstract excerpt
Because glutathione (GSH) is an important antioxidant, we hypothesized that changes in lung and systemic availability of GSH and its precursor amino acid, cysteine, are induced by exposure to hyperoxia and that these changes could be modulated by toxic O2 metabolites. In organs and plasma of mice exposed to hyperoxia, we measured GSH and sulfur-containing amino acids (SAAs), the latter by capillary gas...
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