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Article

Evaluation of polymorphic splicing in the mechanism of the association of the insulin gene with diabetes.

Diabetes - 1 Mar 2007

Marchand Luc, Polychronakos Constantin

Abstract excerpt

The association of type 1 diabetes with the insulin gene (IDDM2 locus) has been mapped to a short haplotype encompassing two single nucleotide polymorphisms (SNPs) in perfect linkage disequilibrium (r(2) = 1) with each other and with the two allele classes at the variable number of tandem repeats (VNTR) polymorphism upstream of the transcription site. Although it is believed that the genetic effect is mediated...

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Source

Identifiers

PMID: 17327440
DOI: 10.2337/db06-0402

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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