Article
Association of genotypes of thrombin-activatable fibrinolysis inhibitors with thrombotic microangiopathies--a pilot study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 May 2007
Sucker Christoph, Hetzel Gerd Ruediger, Farokhzad Firuseh, Dahhan Fieras, Schmitz Michael, Kurschat Christine, Grabensee Bernd, Maruhn-Debowski Beate, Zotz Rainer, Scharf Ruediger
Abstract excerpt
BACKGROUND: Thrombotic microangiopathies are characterized by microvascular thrombosis, consequently leading to microangiopathic haemolytic anaemia, thrombocytopenia and organ dysfunction. Although recent research has elucidated the pathogenesis of these rare thrombotic disorders to some extent, the determinants contributing to the manifestation remain rather unclear in the majority of affected patients. METHOD:...
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