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Article

Molecular basis of thrombotic microangiopathy.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2025

Zhou Yuan, Moake Joel, Dong Jing-Fei

Abstract excerpt

Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome are 2 index conditions of thrombotic microangiopathy (TMA). While conditions classified as TMA share common clinical characteristics, their underlying causes differ significantly. TMA is challenging to diagnose but life threating without proper and timely diagnosis and treatments. In this review, we discussed recent advances in understanding of the...

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Identifiers

PMID: 40541812
DOI: 10.1016/j.jtha.2025.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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