Thrombophilia: an expanding group of genetic defects that predispose to thrombosis.

Abstract excerpt

Thrombophilia is a term recently coined to describe the increased tendency of some patients to develop thrombosis. Although the term was originally used as a clinical description, the abnormalities of the coagulation system responsible can now be identified in approximately 50% of cases of thrombosis. Many of these disorders are hereditary and it is this group that are generally referred to as thrombophilia....

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