Article
An overview of genetic risk factors in thrombophilia.
Srpski arhiv za celokupno lekarstvo - 1 Jan 2010
Djordjević Valentina, Rakićević Ljiljana, Radojković Dragica
Abstract excerpt
Thrombophilia is a multifactorial disorder, involving both genetic and acquired risk factors that affect the balance between procoagulant and anticoagulant factors and lead to increased tendency to thrombosis. The concept that thrombophilia could be associated with genetic defects was first proposed in 1965 after the discovery of familiar antihrombin III deficiency. Further family studies showed that deficiency...
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