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Article

Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

Hepatology (Baltimore, Md.) - 1 Mar 2007

Martin Pascal G P, Guillou Hervé, Lasserre Frédéric, Déjean Sébastien, Lan Annaig, Pascussi Jean-Marc, Sancristobal Magali, Legrand Philippe, Besse Philippe, Pineau Thierry

Abstract excerpt

UNLABELLED: Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a major transcriptional regulator of lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates the expression of numerous genes in organs displaying high FA catabolic rates, including the liver. The role of this nuclear receptor as a sensor of whole dietary fat intake has been inferred, mostly from...

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Identifiers

PMID: 17326203
DOI: 10.1002/hep.21510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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