Article
Genetic and diet effects on Ppar-α and Ppar-γ signaling pathways in the Berlin Fat Mouse Inbred line with genetic predisposition for obesity.
Lipids in health and disease - 10 Sept 2010
Wagener Asja, Goessling Helge F, Schmitt Armin O, Mauel Susanne, Gruber Achim D, Reinhardt Richard, Brockmann Gudrun A
Abstract excerpt
BACKGROUND: The Berlin Fat Mouse Inbred (BFMI) line is a new mouse model for obesity, which was long-term selected for high fatness. Peroxisome proliferator-activated receptors (PPARs) are involved in the control of energy homeostasis, nutrient metabolism and cell proliferation. Here, we studied the expression patterns of the different Ppar genes and the genes in the PPAR pathway in the BFMI line in comparison to...
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