Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peroxisome proliferator-activated receptors as molecular targets in relation to obesity and type 2 diabetes.

Pharmacogenomics - 1 Jun 2007

Seda Ondørej, Sedová Lucie

Abstract excerpt

The three isotypes of peroxisome proliferator-activated receptors (PPARs) are currently perceived as major regulatory nodes (or hubs) of metabolic pathway networks, linking most prevalent diseases including Type 2 diabetes, obesity, dyslipidemia and atherosclerosis. The integrative functions of PPARs are also reflected in their ecogenetic profile, when the variants underlying pharmacogenetic interactions were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Drug Delivery Systems
Share to Gene Targeting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Obesity

Share to Peroxisome Proliferator-Activated Receptors

Source

Identifiers

PMID: 17559348
DOI: 10.2217/14622416.8.6.587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peroxisome proliferator-activated receptors as molecular targets in relation to obesity and type 2 diabetes.PMID 17559348Read ↗

Role of peroxisome proliferator-activated receptors gene polymorphisms in type 2 diabetes and metabolic syndromeSemantic proximity Read ↗

Roles of PPARs in health and diseaseSemantic proximity Read ↗

Peroxisome proliferator activated receptors and obesity.Semantic proximity Read ↗

Gene-Nutrient Interaction in Type 2 Diabetes: An Appraisal of the Role of the Peroxisome Proliferator-Activated Receptor Pathway.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology.Semantic proximity Read ↗

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.Semantic proximity Read ↗

PPARγ and metabolism: insights from the study of human genetic variantsSemantic proximity Read ↗

PPAR gamma as a metabolic regulator: insights from genomics and pharmacology.Semantic proximity Read ↗

Peroxisome Proliferator-Activated Receptor-γ: Master Regulator of Adipogenesis and ObesitySemantic proximity Read ↗

PPARs and their Effects on the Cardiovascular SystemSemantic proximity Read ↗

PPARs: Regulators of Metabolism and As Therapeutic Targets in Cardiovascular disease. Part I: PPAR-αSemantic proximity Read ↗

Peroxisome Proliferator-Activated Receptors (PPARs) and Oxidative Stress in Physiological Conditions and in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.