Article
Shorter CAG repeat length in the AR gene is associated with poor outcome in head and neck cancer.
Archives of oral biology - 1 Aug 2007
Rosa Fabíola Encinas, dos Santos Rodrigo Mattos, Poli-Frederico Regina Célia, Canevari Renata de Azevedo, Nishimoto Inês Nobuko, Magrin José, Rainho Cláudia Aparecida, Kowalski Luiz Paulo, Rogatto Silvia Regina
Abstract excerpt
OBJECTIVE: Alterations in the size of the [CAG](n) repeats of the AR gene have been described in several types tumors. The purpose of this study was to evaluate if there is an association between the AR [CAG](n) repeat alleles and the relative risk for head and neck cancer and to analyse microsatellite instability (MSI) and loss of heterozygosity (LOH) in these tumors. DESIGN: Matched samples of blood and head...
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