Article
[Genetic epidemiology of rheumatoid arthritis: what to expect from Latin America?].
Biomedica : revista del Instituto Nacional de Salud - 1 Dec 2006
Delgado-Vega Angélica María, Martín Javier, Granados Julio, Anaya Juan Manuel
Abstract excerpt
Rheumatoid arthritis is a chronic and systemic autoimmune disease characterized by inflammation and destruction of the synovial joints. It affects approximately 0.5% of the Latin-American population and is three times more common in women than in men. Evidence of familial aggregation (lambdas=2-17) was the first indication of a genetic susceptibility to disease. As in other autoimmune diseases, it has a complex...
Topics
- Arthritis, Rheumatoid
- Epidemiologic Studies
- Genetic Predisposition to Disease
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Latin America