Article
Neuronal death in Drosophila triggered by GAL4 accumulation.
The European journal of neuroscience - 1 Feb 2007
Rezával Carolina, Werbajh Santiago, Ceriani María Fernanda
Abstract excerpt
The GAL4/UAS system has been extensively employed in Drosophila to control gene expression in defined spatial patterns. More recently this system has been successfully applied to express genes involved in neurodegeneration to model various diseases in the fruit fly. We used transgenic lines expressing different levels of GAL4 in a particular subset of neurons involved in the control of rhythmic behaviour, so that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
