Article
Progressive neurodegeneration in Drosophila: a model system.
Journal of neural transmission. Supplementum - 1 Jan 2003
Tschäpe J A, Bettencourt da Cruz A, Kretzschmar D
Abstract excerpt
The Drosophila model system has been used to study neurodegenerative diseases by expression of human disease genes in transgenic flies. A different approach is to isolate and characterize Drosophila mutants with progressive neurodegeneration to find novel genes required for brain integrity. Mammalian homologues of these genes might be the genetic basis for some of the various progressive neurodegeneration...
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