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Article

A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.

Journal of cancer research and clinical oncology - 1 May 2004

Matsumura Shunji, Oue Naohide, Kitadai Yasuhiko, Chayama Kazuaki, Yoshida Kazuhiro, Yamaguchi Yoshiyuki, Toge Tetsuya, Imai Kazue, Nakachi Kei, Yasui Wataru

Abstract excerpt

PURPOSE: Matrix metalloproteinase-1 (MMP-1) plays a key role in cancer invasion and metastasis by degradation of extracellular matrix (ECM) and basement membrane barriers. The 1G/2G single nucleotide polymorphism (SNP) in the MMP-1 promoter at position -1607 bp has been reported to affect the transcriptional activity. In the light of these findings, we investigated whether this SNP in the MMP-1 promoter is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14986114
DOI: 10.1007/s00432-004-0543-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.PMID 14986114Read ↗

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