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Article

WNK4, as thiazides, shuts off NaCl reabsorption to stimulate Na/K exchange.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 May 2007

Verrey Francois

Abstract excerpt

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Topics

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Share to Blood Pressure
Share to Absorption
Share to Diuretics
Share to Hyperkalemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Tubules, Distal

Share to Sodium Chloride

Share to Sodium Chloride Symporters

Share to Sodium-Potassium-Exchanging ATPase

Source

Identifiers

PMID: 17308320
DOI: 10.1093/ndt/gfm010

Genes

WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

WNK4, as thiazides, shuts off NaCl reabsorption to stimulate Na/K exchange.PMID 17308320Read ↗

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretionSemantic proximity Read ↗

WNK kinases and renal sodium transport in health and disease: an integrated view.Semantic proximity Read ↗

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WNK kinases and the kidney.Semantic proximity Read ↗

Cellular mechanisms of WNK4-mediated regulation of ion transport proteins in the distal tubule.Semantic proximity Read ↗

Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension.Semantic proximity Read ↗

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway.Semantic proximity Read ↗

WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron.Semantic proximity Read ↗

WNKs: protein kinases with a unique kinase domain.Semantic proximity Read ↗

Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.Semantic proximity Read ↗

WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination.Semantic proximity Read ↗

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.Semantic proximity Read ↗

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