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Article

Clonal diversification in OspA-specific antibodies from peripheral circulation of a chronic Lyme arthritis patient.

Journal of immunological methods - 10 Apr 2007

Ghosh Srimoyee, Huber Brigitte T

Abstract excerpt

Chronic, antibiotic treatment-resistant Lyme arthritis develops in a subset of patients following infection with the tick-borne spirochete Borrelia burgdorferi and persists after apparent microbial clearance. IgG responses to Outer Surface Protein (Osp) A, an abundant spirochetal lipoprotein, correlate with both severity and duration of joint inflammation. Characterization of this OspA-directed antibody response...

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Share to Antibodies, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17307198
DOI: 10.1016/j.jim.2007.01.007
PMCID: PMC1899465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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