Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement factor H polymorphism p.Tyr402His and cuticular Drusen.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007

Grassi Michael A, Folk James C, Scheetz Todd E, Taylor Christine M, Sheffield Val C, Stone Edwin M

Abstract excerpt

OBJECTIVE: To determine the histidine frequency in patients with the cuticular drusen phenotype of age-related macular degeneration (AMD). METHODS: Fifty individuals were identified who met the criteria for the cuticular drusen phenotype using a standard threshold photograph. We genotyped DNA samples using a polymerase chain reaction-based restriction digest assay. Seven hundred individuals with typical AMD and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Macular Degeneration

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Retinal Drusen

Source

Identifiers

PMID: 17210858
DOI: 10.1001/archopht.125.1.93

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement factor H polymorphism p.Tyr402His and cuticular Drusen.PMID 17210858Read ↗

Clinical phenotypes associated with the complement factor H Y402H variant in age-related macular degeneration.Semantic proximity Read ↗

Analysis of rare variants in the CFH gene in patients with the cuticular drusen subtype of age-related macular degeneration.Semantic proximity Read ↗

Complement factor H polymorphism in age-related macular degeneration.Semantic proximity Read ↗

Analysis of the Y402H variant of the complement factor H gene in age-related macular degeneration.Semantic proximity Read ↗

Complement factor H 402H variant and reticular macular disease.Semantic proximity Read ↗

Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population.Semantic proximity Read ↗

Association analysis of genetic and environmental risk factors in the cuticular drusen subtype of age-related macular degeneration.Semantic proximity Read ↗

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD.Semantic proximity Read ↗

Y402H complement factor H polymorphism associated with exudative age-related macular degeneration in the French population.Semantic proximity Read ↗

A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration.Semantic proximity Read ↗

Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.Semantic proximity Read ↗

An analysis of the CFH Y402H genotype in AMD patients and controls from the UK, and response to PDT treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.