Article
Structural alterations in outer arms of IgG oligosaccharides in patients with Werner syndrome.
Experimental gerontology - 1 Jun 2007
Kuroda Yasuhiro, Shikata Kohdoh, Takeuchi Fujio, Akazawa Tomomi, Kojima Naoya, Nakata Munehiro, Mizuochi Tsuguo, Goto Makoto
Abstract excerpt
Werner syndrome (WS) is a heredofamilial disorder characterized by clinicopathological premature aging. In healthy individuals, structural alteration of serum IgG oligosaccharides is known to be an aging phenotype. In the present study, we determined and compared oligosaccharide structures of serum IgG among WS patients, healthy age-sex-matched individuals, and healthy elderly individuals from both sexes in order...
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