Article
Mechanism of molecular recognition. Structural aspects of 3,3'-diiodo-L-thyronine binding to human serum transthyretin.
The Journal of biological chemistry - 5 Jan 1992
Wojtczak A, Luft J, Cody V
Abstract excerpt
The three-dimensional structure of the thyroid hormone metabolite, 3,3'-diiodo-L-thyronine (3,3'-T2), complex with human serum transthyretin (TTR) has been refined to R = 18.5% for 8-2 A resolution data. This is the first detailed description of a thyroid hormone metabolite binding to a thyroid t...
Topics
- Binding Sites
- Computer Simulation
- Crystallization
- Diiodothyronines
- Electrons
- Humans
- Molecular Conformation
- Mutation
- Prealbumin