Article
No association between the glutamate decarboxylase 67 gene (GAD1) and schizophrenia in the Japanese population.
Schizophrenia research - 1 Mar 2007
Ikeda Masashi, Ozaki Norio, Yamanouchi Yoshio, Suzuki Tatsuyo, Kitajima Tsuyoshi, Kinoshita Yoko, Inada Toshiya, Iwata Nakao
Abstract excerpt
Postmortem studies regarding schizophrenia revealed altered expression of genes related to gamma-amino butyric acid neurotransmission system. One of the most consistent findings is the reduced level of 67 kDa glutamic acid decarboxylase isoform (GAD(67)). Moreover, several studies reported positive associations between the GAD(67) gene (GAD1) and schizophrenia. These reasons, motivated us to carry out replication...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
