Article
No genetic association between the SLC1A2 gene and Japanese patients with schizophrenia.
Neuroscience letters - 9 Oct 2009
Nagai Yasuhito, Ohnuma Tohru, Karibe Jun, Shibata Nobuto, Maeshima Hitoshi, Baba Hajime, Hatano Tokiko, Hanzawa Ryo, Arai Heii
Abstract excerpt
Glutamatergic dysfunction may be a pathophysiological feature in the brains of schizophrenic patients. In addition to glutamate receptors, excitatory amino acid transporters (EAATs) have received much attention because they directly affect glutamatergic neurotransmission by excluding excessive glutamate from the synaptic cleft. Among these, EAAT2 (also known as solute carrier family 1, member 2; SLC1A2) has been...
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