Article
The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk in Polish BRCA1 mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2007
Jakubowska Anna, Gronwald Jacek, Menkiszak Janusz, Górski Bohdan, Huzarski Tomasz, Byrski Tomasz, Edler Lutz, Lubiñski Jan, Scott Rodney J, Hamann Ute
Abstract excerpt
Breast and ovarian cancer penetrance in BRCA1 mutation carriers is estimated to be between 15% and 80% by age 70 years. At present, it is not possible to predict with any certainty who is most likely to develop disease or which age it will develop. Previous studies have tried to correlate the sit...
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