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Article

Association between the RAD51 135 G>C polymorphism and risk of cancer: a meta-analysis of 19,068 cases and 22,630 controls.

PloS one - 1 Jan 2013

Wang Wei, Li Jia-Lin, He Xiao-Feng, Li An-Ping, Cai Yong-Lin, Xu Na, Sun Shu-Mei, Wu Bing-Yi

Abstract excerpt

BACKGROUND: RAD51 135G>C can modify promoter activity and the penetrance of BRCA1/2 mutations, which plays vital roles in the etiology of various cancer. To date, previous published data on the association between RAD51 135G>C polymorphism and cancer risk remained controversial. Recent meta-analysis only analyzed RAD51 135G>C polymorphism with breast cancer risk, but the results were also inconsistent. METHODS: A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24040396
DOI: 10.1371/journal.pone.0075153
PMCID: PMC3767694

Genes

RAD51
BRCA2
BRCA1

Provenance

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Related research

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Association between the RAD51 135 G>C polymorphism and risk of cancer: a meta-analysis of 19,068 cases and 22,630 controls.PMID 24040396Read ↗

RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

RAD51 135G>C polymorphism contributes to breast cancer susceptibility: a meta-analysis involving 26,444 subjects.Semantic proximity Read ↗

Genetic 135G/C polymorphism of RAD51 gene and risk of cancer: a meta-analysis of 28,956 cases and 28,372 controls.Semantic proximity Read ↗

RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies.Semantic proximity Read ↗

135G/C polymorphism in the RAD51 gene and acute myeloid leukemia risk: a meta-analysis.Semantic proximity Read ↗

RAD51 Gene 135G/C polymorphism and the risk of four types of common cancers: a meta-analysis.Semantic proximity Read ↗

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.Semantic proximity Read ↗

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects.Semantic proximity Read ↗

Association between RAD51 135 G/C polymorphism and risk of 3 common gynecological cancers: A meta-analysis.Semantic proximity Read ↗

Relationship between Rad51 G135C and G172T variants and the susceptibility to cancer: a meta-analysis involving 54 case-control studies.Semantic proximity Read ↗

Association between RAD51 gene polymorphism (-135G/C) and susceptibility of myelodysplastic syndrome and acute leukemia: evidence based on a meta-analysis.Semantic proximity Read ↗

RAD51 135G>C does not modify breast cancer risk in non-BRCA1/2 mutation carriers: evidence from a meta-analysis of 12 studies.Semantic proximity Read ↗

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