Article
A single nucleotide polymorphism in the 5' untranslated region of RAD51 and ovarian cancer risk in Polish women.
European journal of gynaecological oncology - 1 Jan 2012
Romanowicz-Makowska H, Smolarz B, Samulak D, Michalska M, Lewy J, Burzyński M, Kokołaszwili G
Abstract excerpt
BACKGROUND: DNA repair gene polymorphisms are known to influence cancer risk. The RAD51 gene encodes proteins essential for maintaining genomic stability by playing a central role in holmology-dependent recombinational repair of the DNA double-strand breaks. Aims. We investigated the association of polymorphisms in the DNA repair genes RAD51-135G > C and 172G >T with ovarian cancer risk. METHODS: 120 Polish...
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