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Article

Mitochondrial protein import and human health and disease.

Biochimica et biophysica acta - 1 May 2007

MacKenzie James A, Payne R Mark

Abstract excerpt

The targeting and assembly of nuclear-encoded mitochondrial proteins are essential processes because the energy supply of humans is dependent upon the proper functioning of mitochondria. Defective import of mitochondrial proteins can arise from mutations in the targeting signals within precursor proteins, from mutations that disrupt the proper functioning of the import machinery, or from deficiencies in the...

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Identifiers

PMID: 17300922
DOI: 10.1016/j.bbadis.2006.12.002
PMCID: PMC2702852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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