Article
Mitochondrial protein quality control during biogenesis and aging.
Trends in biochemical sciences - 1 May 2011
Baker Brooke M, Haynes Cole M
Abstract excerpt
Mitochondrial dysfunction has long been associated with the aging process and the onset of numerous diseases. Regulation of the complex protein-folding environment within the organelle is essential for maintaining efficient metabolic output. Over time, dysregulation of protein homeostasis arises...
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