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Article

Mitochondrial protein quality control during biogenesis and aging.

Trends in biochemical sciences - 1 May 2011

Baker Brooke M, Haynes Cole M

Abstract excerpt

Mitochondrial dysfunction has long been associated with the aging process and the onset of numerous diseases. Regulation of the complex protein-folding environment within the organelle is essential for maintaining efficient metabolic output. Over time, dysregulation of protein homeostasis arises through stress induced by the accumulation of reactive oxygen species and mutations in the mitochondrial genome...

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PMID: 21353780
DOI: 10.1016/j.tibs.2011.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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