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Role of Mitochondrial Protein Import in Age-Related Neurodegenerative and Cardiovascular Diseases

14 Dec 2021

Abstract excerpt

Mitochondria play a critical role in providing energy, maintaining cellular metabolism, and regulating cell survival and death. To carry out these crucial functions, mitochondria employ more than 1500 proteins, distributed between two membranes and two aqueous compartments. An extensive network of dedicated proteins is engaged in importing and sorting these nuclear-encoded proteins into their designated...

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PMID: 34944035
DOI: 10.3390/cells10123528

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