Article
Metabolic regulation of IMD2 transcription and an unusual DNA element that generates short transcripts.
Molecular and cellular biology - 1 Apr 2007
Kopcewicz Katarzyna A, O'Rourke Thomas W, Reines Daniel
Abstract excerpt
Transcriptional regulation of IMD2 in yeast (Saccharomyces cerevisiae) is governed by the concentration of intracellular guanine nucleotide pools. The mechanism by which pool size is measured and transduced to the transcriptional apparatus is unknown. Here we show that DNA sequences surrounding the IMD2 initiation site constitute a repressive element (RE) involved in guanine regulation that contains a novel...
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