Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline mutations in the BRCA2 gene and susceptibility to hereditary prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2007

Agalliu Ilir, Kwon Erika M, Zadory Daniel, McIntosh Laura, Thompson Joseph, Stanford Janet L, Ostrander Elaine A

Abstract excerpt

PURPOSE: Several epidemiologic studies have reported that carriers of germline mutations in the BRCA2 gene have an increased risk of prostate cancer, with the highest risk observed in men diagnosed at earlier ages. However, studies of the contribution of BRCA2 mutations to the etiology of hereditary prostate cancer (HPC) have been inconsistent. EXPERIMENTAL DESIGN: To further address this issue, 266 subjects from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

Share to Germ-Line Mutation

Share to Introns

Share to Mutation, Missense

Share to Prostatic Neoplasms

Source

Identifiers

PMID: 17289875
DOI: 10.1158/1078-0432.CCR-06-2164

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline mutations in the BRCA2 gene and susceptibility to hereditary prostate cancer.PMID 17289875Read ↗

The role of the BRCA2 gene in susceptibility to prostate cancer revisited.Semantic proximity Read ↗

Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer.Semantic proximity Read ↗

The role of BRCA1 and BRCA2 in prostate cancer.Semantic proximity Read ↗

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.Semantic proximity Read ↗

The relevance of BRCA genetics to prostate cancer pathogenesis and treatment.Semantic proximity Read ↗

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.Semantic proximity Read ↗

BRCA2 gene mutation and prostate cancer risk. Comprehensive review and update.Semantic proximity Read ↗

Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer.Semantic proximity Read ↗

BRCA1 and BRCA2 have a limited role in familial prostate cancer.Semantic proximity Read ↗

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.Semantic proximity Read ↗

Germline BRCA mutation in male carriers-ripe for precision oncology?Semantic proximity Read ↗

Prostate Cancer Risk by BRCA2 Genomic Regions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.