Article
BRCA1 and BRCA2 have a limited role in familial prostate cancer.
Cancer research - 1 Mar 2000
Sinclair C S, Berry R, Schaid D, Thibodeau S N, Couch F J
Abstract excerpt
Epidemiological studies have suggested that the breast cancer susceptibility genes, BRCA1 and BRCA2, may be involved in the development of prostate cancer. Several studies have screened prostate cancer populations for the presence of BRCA1 and BRCA2 mutations, with few mutations identified. In this study, 22 high-risk prostate cancer families (at least three cases of prostate cancer) were screened by...
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