Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D

20 Mar 2018

Abstract excerpt

BACKGROUND: Three-dimensional cultures of mammary epithelial cells allow for biologically-relevant studies of the development of the mammary gland in rodents and humans under normal and pathological conditions, like carcinogenesis. Under these conditions, mammotropic hormones play significant roles in tissue morphogenesis. Therefore, a system that recreates the normal, hormonally responsive epithelium would be a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell Adhesion Molecules Research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29559854
DOI: 10.1186/s12935-018-0534-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3DPMID 29559854Read ↗

Three-dimensional culture of human breast epithelial cells: the how and the why.Semantic proximity Read ↗

Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studiesSemantic proximity Read ↗

Transcriptional Factor Repertoire of Breast Cancer in 3D Cell Culture ModelsSemantic proximity Read ↗

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerSemantic proximity Read ↗

Morphometrical, Morphological, and Immunocytochemical Characterization of a Tool for Cytotoxicity Research: 3D Cultures of Breast Cell Lines Grown in Ultra-Low Attachment PlatesSemantic proximity Read ↗

Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells.Semantic proximity Read ↗

Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D CultureSemantic proximity Read ↗

A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumorSemantic proximity Read ↗

The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures.Semantic proximity Read ↗

Phenotypic and functional characterization of two bovine mammary epithelial cell lines in 2D and 3D models.Semantic proximity Read ↗

Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol.Semantic proximity Read ↗

Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.