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Article

Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes

7 Feb 2007

Abstract excerpt

Opsonization of apoptotic cardiocytes by maternal anti-Ro/SSA and anti-La/SSB antibodies contributes to tissue injury in the neonatal lupus syndrome. The objective of the current study was to quantify the surface membrane expression of Ro/La components during different phases of apoptosis and map the Ro/La apotopes (epitopes expressed on apoptotic cells) bound by cognate antibodies. Multi-parameter flow cytometry...

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PMID: 17286801
DOI: 10.1111/j.1365-2249.2007.03331.x

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