Article
Neonatal lupus: advances in understanding pathogenesis and identifying treatments of cardiac disease.
Current opinion in rheumatology - 1 Sept 2012
Izmirly Peter M, Buyon Jill P, Saxena Amit
Abstract excerpt
PURPOSE OF REVIEW: Cardiac manifestations of neonatal lupus include anti-SSA/Ro-SSB/La-mediated conduction system disease and endocardial/myocardial damage resulting in cardiomyopathy. This review will focus on recent data regarding updates on the proposed pathogenesis of disease, morbidity and mortality, and preventive and treatment therapies. RECENT FINDINGS: Evidence from animal models suggests that reactivity...
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