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Article

The role of the IDDM2 locus in the susceptibility of UK APS1 subjects to type 1 diabetes mellitus.

International journal of immunogenetics - 1 Feb 2007

Adamson K A, Cheetham T D, Kendall-Taylor P, Seckl J R, Pearce S H S

Abstract excerpt

Autoimmune polyendocrinopathy syndrome type 1 (APS1) is characterized by autoimmune destruction of endocrine tissues and chronic mucocutaneous candidiasis. Type 1 diabetes (T1D) affects 12-25% of patients with APS1, and the prediction of whether this complication will affect an individual is not currently possible. However, alleles of a variable number tandem repeat (VNTR) 5' of the insulin gene are known to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17284223
DOI: 10.1111/j.1744-313X.2006.00643.x

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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