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Article

HLA class II polymorphism and genetic susceptibility to insulin-dependent diabetes mellitus.

Current topics in microbiology and immunology - 1 Jan 1990

Erlich H A

Abstract excerpt

As we have discussed previously (Horn et al. 1988a; Erlich et al. 1989b; Horn et al. 1988b), there are no unique class II sequences associated with IDDM, which suggests that "normal" class II alleles confer susceptibility. Given the estimates of concordance--under 50% of monozygotic twins and approximately 15% (Tattersol, Pyle 1972 and Thomson 1988) for HLA-identical sibs--, it is not surprising that some...

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Share to Diabetes Mellitus, Type 1
Share to Genes, MHC Class II
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

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Source

Identifiers

PMID: 2127392
DOI: 10.1007/978-3-642-75741-9_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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