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Article

DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia.

Cancer research - 1 Feb 2007

Agrawal Shuchi, Unterberg Matthias, Koschmieder Steffen, zur Stadt Udo, Brunnberg Uta, Verbeek Walter, Büchner Thomas, Berdel Wolfgang E, Serve Hubert, Müller-Tidow Carsten

Abstract excerpt

Epigenetic changes play an important role in leukemia pathogenesis. DNA methylation is among the most common alterations in leukemia. The potential role of DNA methylation as a biomarker in leukemia is unknown. In addition, the lack of molecular markers precludes minimal residual disease (MRD) estimation for most patients with hematologic malignancies. We analyzed the potential of aberrant DNA promoter...

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Share to Acute Disease
Share to Cyclin-Dependent Kinase Inhibitor p15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Estrogen Receptor alpha

Share to Genes, Tumor Suppressor

Share to Leukemia, Myeloid

Share to Neoplasm, Residual

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 17283175
DOI: 10.1158/0008-5472.CAN-06-1681

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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