Article

MRD in Acute Leukemias: Lessons Learned from Acute Promyelocytic Leukemia

2024-08-27

Abstract excerpt

Advances in molecular biology, polymerase chain reaction (PCR), and next-generation sequencing (NGS) have transformed the concept of minimal residual disease (MRD) from a philosophical idea into a measurable reality. Acute promyelocytic leukemia (APL) led the way in this transformation, initially using PCR to detect MRD in patients in remission, and more recently, aiming to eliminate it entirely with modern treatm...

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Literature Corpus work: d71bb0fd-affa-5af3-bfde-65917f563ef3
DOI: 10.20944/preprints202408.1812.v1

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