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Article

Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns.

Leukemia - 1 Jan 2022

Božić Tanja, Kuo Chao-Chung, Hapala Jan, Franzen Julia, Eipel Monika, Platzbecker Uwe, Kirschner Martin, Beier Fabian, Jost Edgar, Thiede Christian, Wagner Wolfgang

Abstract excerpt

Assessment of measurable residual disease (MRD) upon treatment of acute myeloid leukemia (AML) remains challenging. It is usually addressed by highly sensitive PCR- or sequencing-based screening of specific mutations, or by multiparametric flow cytometry. However, not all patients have suitable mutations and heterogeneity of surface markers hampers standardization in clinical routine. In this study, we propose an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

Share to Neoplasm Recurrence, Local

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Source

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Identifiers

PMID: 34131280
DOI: 10.1038/s41375-021-01316-z
PMCID: PMC8727289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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